This book is a life changer. As a student of Buddhism without delving fully into the practice, this was very enlightening to me. The philosophy of accepting what is and limiting suffering combined with the neuroscience of brain chemistry described by the authors in Buddha's Brain are a cogent and helpful guide to life in the 21st century.
The information is contained in four parts: The Causes of Suffering; Love; Happiness; and Wisdom. Each part has chapters that explain why and how to practice retraining your brain toward happiness. Key points are summarized at the end of each chapter.
For those interested, there is a section at the end of nutritional chemistry to bolster your efforts. I'm keeping this one, and recommending it to my friends.